ST. LOUIS--(BUSINESS WIRE)--May 31, 2006--Centene Corporation (NYSE: CNC) today announced that it will webcast its Fourth Annual Investor Day to be held on Tuesday, June 6, 2006, in New York City. The webcast will begin promptly at 8:00 a.m. Eastern Time. At the meeting, Centene expects Michael F. Neidorff, its Chairman and Chief Executive Officer, to make remarks regarding the Company's performance and future prospects.

Institutional investors and analysts interested in attending should contact Lisa M. Wilson for additional information.

Interested parties may listen to the webcast by going to the Company's website at www.centene.com and accessing the Investor Relations section.

About Centene Corporation

Centene Corporation is a leading multi-line healthcare enterprise that provides programs and related services to individuals receiving benefits under Medicaid, including Supplemental Security Income (SSI) and the State Children's Health Insurance Program (SCHIP). The Company operates health plans in Indiana, Kansas, Missouri, New Jersey, Ohio, Texas and Wisconsin. In addition, the Company contracts with other healthcare organizations to provide specialty services including behavioral health, disease management, nurse triage, pharmacy benefit management and treatment compliance. Information regarding Centene is available via the Internet at www.centene.com.

CONTACT: Centene Corporation, St. Louis Lisa M. Wilson, 212-759-3929

SOURCE: Centene Corporation